Manchester United will host Premier League champions Liverpool in the FA Cup fourth round.
Monday night’s draw pitched 12-time winners United into battle with Jurgen Klopp’s men, who beat a coronavirus-hit Aston Villa side to book their place.
National League North side Chorley’s reward for their victory over a depleted Derby was a home tie with Premier League Wolves.
League Two Crawley, who dumped top-flight Leeds out of the competition in the third round, face a trip to Sky Bet Championship promotion hopefuls Bournemouth.
Fourth-tier counterparts Cheltenham, however, were rewarded for their win over Mansfield with a home tie against Premier League giants Manchester City.
Tottenham, 5-0 third-round winners at Marine of the Northern Premier League North West Division, are on the road again, with Championship strugglers Wycombe this time providing the opposition.
Should Chorley pull off a shock against Wolves, they could have another big date ahead of them after the fifth round draw pitched the winners in battle with either Southampton, Shrewsbury or 14-time winners Arsenal.
The victors in the Manchester United v Liverpool showdown will face Stockport, West Ham or Doncaster, while either Wycombe or Tottenham will travel to the winners of the Everton v Sheffield Wednesday tie.